known more fully as New Delhi-Metallo-1 or New Delhi metallo-ß-lactamase-1,
is a serious global, drug-resistant superbug threat. This page
aims to provide you with more information about the bug in a simple,
facts (last updated August 2010):
NDM-1 is known to be hosted by
two different bacteria: the gut bacterium Escherichia coli (E.
coli), and Klebsiella
pneumoniaanother whcih can
invade the lungs.
NDM-1 infects people with weak immune systems, in particular those
who have recently had surgery. Infection can cause wound infections,
septicaemia, pneumonia, gastro-enteritis and even death.
Some strains of NDM-1 are resistant to all known antibiotics and
it is thought that NDM-1 could prove to be more difficult to tackle
than Methicillin Resistant Staphylococcus Aureus (MRSA) or Clostridium
The latest strains of NDM-1, known as enterobacteriaceae, produce
enzymes that counteract carbapenems, some of the most powerful
antibiotics used by doctors to tackle the most virulent infections.
Doctors are worried because the DNA code for the enzymes produced
by NDM-1 could jump from one strain of bacteria to another. If
this were to happen, it could result in highly dangerous infections
which could be spread from person to person.
There is already some evidence of NDM-1 being passed from person
to person in hospitals.
NDM-1 superbug is already widespread in parts of Asia such as
the Indian subcontinent, and has spread to a number of countries
including the US, UK, Canada, Australia and the Netherlands.
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